Repository of Research and Investigative Information

Repository of Research and Investigative Information

دانشگاه علوم پزشکی و خدمات بهداشتی درمانی زنجان

The role of heat shock proteins as chaperones on several human diseases

(2006) The role of heat shock proteins as chaperones on several human diseases. SAUDI MEDICAL JOURNAL. pp. 1302-1305.

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Abstract

Some heat shock proteins (HSPs), act as molecular chaperones. These and other molecular chaperones that are not HSPs, function in a variety of protein biosynthetic event and protect proteins from the deleterious effects of stressors by stabilizing, and refolding proteins. They assist protein folding, assembly, transport and degradation. Several human diseases such as neurodegeneration, cancer, aging, retinal dystrophy, and inflammation arise from defects HSPs and protein folding. This review demonstrates the chaperones such as properties of HSPs in cellular processes and their implication in different kind of human diseases.

Item Type: Article
Page Range: pp. 1302-1305
Journal or Publication Title: SAUDI MEDICAL JOURNAL
Abstract and Indexing: ISI, Pubmed, Scopus
Quartile : Q3
Volume: 27
Number: 9
Publisher: web of science,pubmed,scopus
Depositing User: خانم مریم زرقانی
URI: http://repository.zums.ac.ir/id/eprint/889

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