Repository of Research and Investigative Information

Repository of Research and Investigative Information

دانشگاه علوم پزشکی و خدمات بهداشتی درمانی زنجان

Factors Associated with Thyroid Dysfunction in Hypothyroidism-Endemic Region of Ravansar, 2017-2018: A Cross-Sectional Analysis

(2021) Factors Associated with Thyroid Dysfunction in Hypothyroidism-Endemic Region of Ravansar, 2017-2018: A Cross-Sectional Analysis. Journal of Advances in Medical and Biomedical Research. pp. 145-151. ISSN 2676-6264

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Abstract

Background & Objective: Hypothyroidism is a prevalent condition in various regions all over the world, including Iran. This study aimed to identify the factors associated with thyroid dysfunctions in Ravansar area, Kermanshah province. Due to hypo and hyperthyroidism diversity and pathogeneses complexity, machine learning was also integrated; it is as an accurate and potent method for the dimensionality reduction to realize the study objective. Materials & Methods: In this study, 10069 individuals participated from Ravansar area. Data were taken from the Ravansar Non-Communicable Diseases (RaNCD) cohort study, which is a part of national PERSIAN cohort. Feature selection was done using random forests machine learning tool. The two thyroid diseases correlation was explored through conventional statistical procedures. Results: Female sex was the most significant risk factor for hypothyroidism (OR=6.24, CI: 4.13-9.63; P<0.001). Depression (OR=2.07, CI: 1.34-3.09; P<0.001), age group of 45-55 years (OR=1.56, CI: 1.18-2.07; P<0.01), daily salt consumption of >10 gr (OR=1.87, CI: 1.15-2.90; P<0.01), kidney stone (OR=1.35, CI: 1.02-1.78; P<0.05) and unsaturated fats intake (OR=1.01, CI: 1.00-1.02; P<0.05) were significantly associated with underactive thyroid condition. No significant associated factor was found for hyperthyroidism. Conclusion: Female sex is a global well-established hypothyroidism-associated factor. The results of the present study suggest taking some measures to reduce hypothyroidism, by addressing the intervening factors.

Item Type: Article
Keywords: Hypothyroidism, Hyperthyroidism, Prevalence, Associations, Multifactor dimensionality reduction
Divisions: vice research > Journal of Advances in Medical and Biomedical Research
Page Range: pp. 145-151
Journal or Publication Title: Journal of Advances in Medical and Biomedical Research
Volume: 29
Number: 134
Publisher: Zanjan University of Medical Sciences
Identification Number: https://doi.org/10.30699/jambs.29.134.145
ISSN: 2676-6264
Depositing User: خانم فرزانه محمودوند
URI: http://repository.zums.ac.ir/id/eprint/8012

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