Repository of Research and Investigative Information

Repository of Research and Investigative Information

دانشگاه علوم پزشکی و خدمات بهداشتی درمانی زنجان

The Effect of Ozonated Water and Chlorhexidine Gluconate on Prevention of Ventilator-Associated Pneumonia: A Double-Blind, Randomized, Clinical Trial

(2017) The Effect of Ozonated Water and Chlorhexidine Gluconate on Prevention of Ventilator-Associated Pneumonia: A Double-Blind, Randomized, Clinical Trial. Iranian Red Crescent Medical Journal. p. 8. ISSN 2074-1804

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Abstract

Background: The relationship between the oral care and ventilator-associated pneumonia (VAP) was confirmed in patients undergoing ventilation. Objectives: The current study aimed at investigating the effects of chlorhexidine gluconate (CHX) and ozonated water on the prevention of VAP. Methods: The current double-blind, randomized, clinical trial with the experimental and control groups was conducted in Iran in 2014. In the current study, 75 inpatients undergoing ventilation were grouped through the convenience sampling method and randomly allocated into 2 groups based on the inclusion criteria. In the experimental group (39 patients), oral care provided by ozonated water, while in the control group (35 patients), oral care was provided via CHX. Clinical pulmonary infection score (CPIS) was used to examine the rate of VAP infection. Results: According to the results of the current study, the occurrence rate of VAP in the experimental and control groups were 2.4 and 8.3, respectively that was equal until the 3rd day (P value = 0.339). However, on the 4th day, the VAP occurrence rate in the experimental group (14.6) was significantly lower than that of the control group (30.6) (P value = 0.02). Conclusions: Basedonthe results, ozonated water was more effective to prevent VAP than CHX. Ozone water can be used as a suitable alternative mouthwash in patients undergoing mechanical ventilation.

Item Type: Article
Keywords: Oral Hygiene Chlorhexidine Gluconate Ozone Ventilator-associated Pneumonia Mechanical Ventilation INTENSIVE-CARE-UNIT ORAL CARE MECHANICAL VENTILATION OZONE METAANALYSIS HYGIENE MOUTHWASH INFECTION PROGRAM ICU Medicine, General & Internal
Page Range: p. 8
Journal or Publication Title: Iranian Red Crescent Medical Journal
Abstract and Indexing: ISI, Scopus
Quartile : Q4
Volume: 19
Number: 10
Identification Number: https://doi.org/10.5812/ircmj.60576 <Go to ISI>://WOS:000418479600019
ISSN: 2074-1804
Depositing User: خانم مریم زرقانی
URI: http://repository.zums.ac.ir/id/eprint/80

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