Repository of Research and Investigative Information

Repository of Research and Investigative Information

دانشگاه علوم پزشکی و خدمات بهداشتی درمانی زنجان

The impact of laparoscopic cystectomy on ovarian reserve in patients with unilateral and bilateral endometrioma

(2017) The impact of laparoscopic cystectomy on ovarian reserve in patients with unilateral and bilateral endometrioma. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics. pp. 200-204. ISSN 1879-3479 (Electronic) 0020-7292 (Linking)

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Abstract

OBJECTIVE: To evaluate the effects of laparoscopic cystectomy on serum anti-Mullerian hormone (AMH) level as a marker of ovarian reserve in patients with endometrioma. METHODS: A prospective observational study enrolled patients aged younger than 40 years who were referred to a tertiary center in Tehran, Iran, between January 1, 2013 and December 31, 2014 to undergo laparoscopic cystectomy for ovarian endometriomas at least 30 mm in diameter, or regardless of size for patients with infertility, dysmenorrhea, dyspareunia, or dyschezia. Baseline and 6-month post-operative AMH levels were compared. RESULTS: Data from 70 patients were included in the analyses. Among patients with unilateral endometriomas, lower pre-operative AMH levels were observed in patients with endometriomas at least 50 mm in diameter (P=0.027), whereas cyst size was not associated with differences in pre-operative AMH level in patients with bilateral endometriomas (P=0.227). Across the entire study population, post-operative AMH levels were lower than the baseline (P=0.008). Greater post-operative decreases in AMH were associated with bilateral cysts compared with unilateral cysts (P=0.046), cysts being at least 50 mm in diameter among patients with unilateral cysts (P=0.028), and both cysts being at least 50 mm in diameter among patients with bilateral cysts (P=0.025). CONCLUSION: Laparoscopic cystectomy was associated with post-operative decreases in serum AMH, particularly with bilateral involvement and endometriomas at least 50 mm in diameter.

Item Type: Article
Keywords: Adult Anti-Mullerian Hormone/*blood Biomarkers/blood Cystectomy/*adverse effects Endometriosis/*surgery Female Humans Iran Laparoscopy/*adverse effects Ovarian Cysts/*surgery *Ovarian Reserve Postoperative Period Prospective Studies Tertiary Care Centers Young Adult *Anti-Mullerian hormone *Endometrioma *Laparoscopic cystectomy
Page Range: pp. 200-204
Journal or Publication Title: International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
Abstract and Indexing: ISI, Pubmed, Scopus
Quartile : Q2
Volume: 136
Number: 2
Identification Number: https://doi.org/10.1002/ijgo.12046
ISSN: 1879-3479 (Electronic) 0020-7292 (Linking)
Depositing User: خانم مریم زرقانی
URI: http://repository.zums.ac.ir/id/eprint/627

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