Repository of Research and Investigative Information

Repository of Research and Investigative Information

دانشگاه علوم پزشکی و خدمات بهداشتی درمانی زنجان

Diversity and ecotypic variation in the antioxidant and antigenotoxic effects of Thymus kotschyanus Boiss & Hohen

(2016) Diversity and ecotypic variation in the antioxidant and antigenotoxic effects of Thymus kotschyanus Boiss & Hohen. Flavour and Fragrance Journal. pp. 429-437. ISSN 0882-5734

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Official URL: <Go to ISI>://WOS:000385712600003

Abstract

Thymus species are amongst the most popular medicinal plants because of their biological effects and pharmacological properties, and they are widely used in folk medicine for many disorders. Fourteen ecotypic Thymus kotschyanus essential oils were isolated, and the biological functionalities of ecotypic oils were characterized in terms of free radical scavenging and antigenotoxic properties. The most abundant ecotypic oil constituents were thymol and carvacrol (27.2-75.6). The oils produced scavenging capacity, bleaching inhibitory capacity, and COMET-inhibitory capacity values in a dose-dependent manner ranging from 0.15 to 4.79 mg/ml, 0.04 to 3.1 mg/ml and 0.03 to 5.00 mg/ml, respectively. The benefits of T. kotschyanus essential oils from different regions vary, and they represent an inexpensive source of natural substances that have the potential to be used as antioxidative and antigenotoxic agents. Although the impacts of the microenvironment, climate difference and agronomical condition on the medical benefits of the plant were complex and highly context dependent, some correlations among the biological effects, main essential constituents, and the geographical environment were predicted. Copyright (c) 2016 John Wiley & Sons, Ltd.

Item Type: Article
Keywords: antigenotoxicity antioxidant essential oil geographical variation Thymus kotschyanus ESSENTIAL-OILS CLIMATE-CHANGE ANTIBACTERIAL FOODS GENOTOXICITY SPICES PLANTS HERBS Chemistry, Applied Food Science & Technology
Page Range: pp. 429-437
Journal or Publication Title: Flavour and Fragrance Journal
Abstract and Indexing: ISI
Quartile : Q2
Volume: 31
Number: 6
Identification Number: https://doi.org/10.1002/ffj.3333
ISSN: 0882-5734
Depositing User: خانم مریم زرقانی
URI: http://repository.zums.ac.ir/id/eprint/473

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