Repository of Research and Investigative Information

Repository of Research and Investigative Information

دانشگاه علوم پزشکی و خدمات بهداشتی درمانی زنجان

Theoretical and Experimental Solubility of Celecoxib in Binary and Ternary Solvents of Polyethylene Glycols 200, 400 or 600 with Ethanol and Water at 298.2 K

(2016) Theoretical and Experimental Solubility of Celecoxib in Binary and Ternary Solvents of Polyethylene Glycols 200, 400 or 600 with Ethanol and Water at 298.2 K. Journal of Solution Chemistry. pp. 1797-1810. ISSN 0095-9782

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Official URL: <Go to ISI>://WOS:000388183300011

Abstract

The solubilities of celecoxib in the binary and ternary mixtures of polyethylene glycols 200, 400 or 600 with ethanol and water (185 data points) at 298.2 K were determined and mathematically represented by cosolvency models. The obtained overall mean relative deviations (OMRDs) for fitting the solubility data of celecoxib in binary and ternary mixtures using the Jouyban-Acree model for the binary and ternary data sets are 14.7 and 25.8 respectively, and the OMRD values for predicting the solubility data of celecoxib by the trained versions of the Jouyban-Acree model for the binary and ternary data sets of PEG 200, 400 and 600 with ethanol and water are 18.2, 21.3 and 37.9, respectively.

Item Type: Article
Keywords: Celecoxib Solubility Binary and ternary solvent mixtures Modeling Jouyban-Acree model Hansen solubility parameters JOUYBAN-ACREE MODEL N-METHYL-PYRROLIDONE POORLY SOLUBLE DRUG DISSOLUTION RATE PROPYLENE-GLYCOL PLUS WATER MIXTURES INDOMETHACIN DISPERSIONS PREDICTION Chemistry, Physical
Page Range: pp. 1797-1810
Journal or Publication Title: Journal of Solution Chemistry
Abstract and Indexing: ISI, Scopus
Quartile : Q4
Volume: 45
Number: 12
Identification Number: https://doi.org/10.1007/s10953-016-0543-1
ISSN: 0095-9782
Depositing User: خانم مریم زرقانی
URI: http://repository.zums.ac.ir/id/eprint/463

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