Repository of Research and Investigative Information

Repository of Research and Investigative Information

دانشگاه علوم پزشکی و خدمات بهداشتی درمانی زنجان

Piroxicam Solubility in Binary and Ternary Solvents of Polyethylene Glycols 200 or 400 with Ethanol and Water at 298.2 K: Experimental Data Report and Modeling

(2015) Piroxicam Solubility in Binary and Ternary Solvents of Polyethylene Glycols 200 or 400 with Ethanol and Water at 298.2 K: Experimental Data Report and Modeling. JOURNAL OF SOLUTION CHEMISTRY. pp. 1407-1423.

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Abstract

The solubilities of piroxicam in binary and ternary mixtures of polyethylene glycols 200 or 400 with ethanol and water (138 data points) at 298.2 K were determined and mathematically represented by cosolvency models. The solubilities were measured using the shake flask method and the models are used to fit the solubility data of piroxicam in the solvent mixtures. The overall mean relative deviations (OMRDs %) for fitting the solubility data of piroxicam in binary and ternary mixtures using the Williams-Amidon and Jouyban-Acree models are 30.7 and 26.8 %, respectively, and the OMRD % values for predicting the solubilities of piroxicam by the trained versions of the Jouyban-Acree model is 57.3 %.

Item Type: Article
Keywords: Piroxicam; Solubility; Binary and ternary solvent mixtures; Williams-Amidon model; Jouyban-Acree model
Page Range: pp. 1407-1423
Journal or Publication Title: JOURNAL OF SOLUTION CHEMISTRY
Abstract and Indexing: ISI, Scopus
Quartile : Q4
Volume: 44
Number: 7
Publisher: web of science
Depositing User: خانم مریم زرقانی
URI: http://repository.zums.ac.ir/id/eprint/2888

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