Repository of Research and Investigative Information

Repository of Research and Investigative Information

دانشگاه علوم پزشکی و خدمات بهداشتی درمانی زنجان

PHYSICAL ACTIVITY AND BETA-AMYLOID PATHOLOGY IN ALZHEIMER'S DISEASE: A SOUND MIND IN A SOUND BODY

(2017) PHYSICAL ACTIVITY AND BETA-AMYLOID PATHOLOGY IN ALZHEIMER'S DISEASE: A SOUND MIND IN A SOUND BODY. Excli Journal. pp. 959-972. ISSN 1611-2156

Full text not available from this repository. (Request a copy)

Official URL: http://apps.webofknowledge.com/full_record.do?prod...

Abstract

Alzheimer's disease (AD) is the most common type of dementia worldwide. Since curative treatment has not been established for AD yet and due to heavy financial and psychological costs of patients' care, special attention has been paid to preventive interventions such as physical activity. Evidence shows that physical activity has protective effects on cognitive function and memory in AD patients. Several pathologic factors are involved in AD-associated cognitive impairment some of which are preventable by physical activity. Also, various experimental and clinical studies are in progress to prove exercise role in the beta-amyloid (A beta) pathology as a most prevailing hypothesis explaining AD pathogenesis. This study aims to review the role of physical activity in A beta-related pathophysiology in AD.

Item Type: Article
Keywords: physical activity Alzheimer's disease beta-amyloid prevention INSULIN-DEGRADING ENZYME MILD COGNITIVE IMPAIRMENT APP/PS1 TRANSGENIC MICE HUMAN APOLIPOPROTEIN-E A-BETA PATHOGENIC PHENOTYPES MOLECULAR-MECHANISMS THERAPEUTIC TARGET HEALTHY ELDERS SENILE PLAQUES Biology
Page Range: pp. 959-972
Journal or Publication Title: Excli Journal
Abstract and Indexing: ISI, Pubmed, Scopus
Quartile : Q2
Volume: 16
Identification Number: https://doi.org/10.17179/excli2017-475 <Go to ISI>://WOS:000406272100024
ISSN: 1611-2156
Depositing User: خانم مریم زرقانی
URI: http://repository.zums.ac.ir/id/eprint/218

Actions (login required)

View Item View Item