Repository of Research and Investigative Information

Repository of Research and Investigative Information

دانشگاه علوم پزشکی و خدمات بهداشتی درمانی زنجان

Comparison of pregnancy outcome in half-dose Triptorelin and short-acting Decapeptyl in long protocol in ART cycles: A randomized clinical trial

(2013) Comparison of pregnancy outcome in half-dose Triptorelin and short-acting Decapeptyl in long protocol in ART cycles: A randomized clinical trial. IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE. pp. 133-138.

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Abstract

Background: Gonadotrophin-releasing hormone (GnRH) agonist is used for controlling ovarian stimulation in assisted reproductive technology (ART) cycles which has some benefits. Objective: To compare the efficacy of two different formulations of GnRH agonist: short-acting and long-acting, for ART protocols. Materials and Methods: In a prospective randomized study, one hundred women who underwent ART cycles were randomly divided into two groups. In group I, the patients received one single injection of 1.87 mg Triptorelin in previous mid-luteal phase. In group II, Decapeptyl 0.1 mg per day started from previous mid-luteal phase. Pregnancy outcome in in vitro fertilization (IVF) cycle was compared between two groups. Results: There were no statistically significant differences in the number of retrieved oocyte (p=0.545), fertilization (p=0.876), implantation (p=0.716) and pregnancy rate (p=0.727) between the two groups. Conclusion: There were not any advantages in IVF outcome between half-dose long-acting and short-acting GnRH agonist groups in ART cycle.

Item Type: Article
Keywords: Author Keywords:Infertility; GnRH agonist; In vitro fertilization; Pregnancy outcome; Decapeptyl KeyWords Plus:IN-VITRO FERTILIZATION; OVARIAN STIMULATION; HORMONE AGONIST; PITUITARY SUPPRESSION; LEUPROLIDE ACETATE; DEPOT TRIPTORELIN; GNRH ANTAGONIST; SINGLE; IVF; RECOMBINANT
Page Range: pp. 133-138
Journal or Publication Title: IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE
Abstract and Indexing: ISI, Pubmed, Scopus
Quartile : Q4
Volume: 11
Number: 2
Publisher: web of science,pubmed,scopus
Depositing User: خانم مریم زرقانی
URI: http://repository.zums.ac.ir/id/eprint/1782

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