Repository of Research and Investigative Information

Repository of Research and Investigative Information

دانشگاه علوم پزشکی و خدمات بهداشتی درمانی زنجان

Copolymers: efficient carriers for intelligent nanoparticulate drug targeting and gene therapy

(2012) Copolymers: efficient carriers for intelligent nanoparticulate drug targeting and gene therapy. Macromol Biosci. pp. 144-164.

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Abstract

Copolymers are among the most promising substances used in the preparation of drug/gene delivery systems. Different categories of copolymers, including block copolymers, graft copolymers, star copolymers and crosslinked copolymers, are of interest in drug delivery. A variety of nanostructures, including polymeric micelles, polymersomes and hydrogels, have been prepared from copolymers and tested successfully for their drug delivery potential. The most recent area of interest in this field is smart nanostructures, which benefit from the stimuli-responsive properties of copolymeric moieties to achieve novel targeted drug delivery systems. Different copolymer applications in drug/gene delivery using nanotechnology-based approaches with particular emphasis on smart nanoparticles are reviewed.

Item Type: Article
Keywords: Animals,Drug Delivery Systems/*methods,Gene Transfer Techniques,Humans,Hydrogels/*chemistry,Hydrogen-Ion Concentration,Hydrophobic and Hydrophilic Interactions,Micelles,Molecular Targeted Therapy,Nanoparticles,Nanotechnology/*methods,Polymers/*chemistry,Temperature,Thermodynamics
Page Range: pp. 144-164
Journal or Publication Title: Macromol Biosci
Abstract and Indexing: ISI, Pubmed
Quartile : Q2
Volume: 12
Number: 2
Publisher: pubmed
Depositing User: خانم مریم زرقانی
URI: http://repository.zums.ac.ir/id/eprint/1603

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