Repository of Research and Investigative Information

Repository of Research and Investigative Information

دانشگاه علوم پزشکی و خدمات بهداشتی درمانی زنجان

Association Between Polycystic Ovarian Syndrome, Overweight, and Metabolic Syndrome in Adolescents

(2012) Association Between Polycystic Ovarian Syndrome, Overweight, and Metabolic Syndrome in Adolescents. JOURNAL OF PEDIATRIC AND ADOLESCENT GYNECOLOGY. pp. 208-212.

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Abstract

Purpose: Polycystic syndrome (PCOS) is associated with multiple metabolic abnormalities. Studies in the adolescent population are still limited and the results have been much different. The aim of this study was to investigate the association between PCOS, overweight, and metabolic syndrome in adolescents. Methods: 30 PCOS adolescents were randomly selected from a PCOS population with NIH 1990 criteria and 71 adolescents from the normal adolescents. Anthropometric, hormonal and metabolic parameters were evaluated in four sub-groups including obese and non-obese PCOS and obese and non-obese normal adolescents. Results: The prevalence of overweight and metabolic syndrome in adolescents with PCOS was 52% and 33.3% respectively vs 22.4% (P = 0.005) and 11.26% in control (normal) adolescents (P = 0.0001). Among all subjects, including obese and non-obese adolescents with or without PCOS, the prevalence of insulin resistance, hypercholesterolemia, central obesity, and metabolic syndrome was higher in obese PCOS with 61.5%, 46.2%, 53.8%, and 69.2%, respectively. Conclusions: Obesity and IR are important risk factors for metabolic syndrome in PCOS. Considering the long-term health risks, it is necessary to identify metabolic disorders in adolescents with PCOS as early as possible.

Item Type: Article
Keywords: Metabolic abnormalities; Polycystic ovary syndrome; Adolescents
Page Range: pp. 208-212
Journal or Publication Title: JOURNAL OF PEDIATRIC AND ADOLESCENT GYNECOLOGY
Abstract and Indexing: ISI, Pubmed, Scopus
Quartile : Q3
Volume: 25
Number: 3
Publisher: web of science,pubmed,scopus
Depositing User: خانم مریم زرقانی
URI: http://repository.zums.ac.ir/id/eprint/1495

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