Repository of Research and Investigative Information

Repository of Research and Investigative Information

دانشگاه علوم پزشکی و خدمات بهداشتی درمانی زنجان

Nasal eosinophilia as a marker for allergic rhinitis: A controlled study of 50 patients

(2012) Nasal eosinophilia as a marker for allergic rhinitis: A controlled study of 50 patients. ENT-EAR NOSE & THROAT JOURNAL. pp. 122-124.

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Abstract

Eosinophils are the principal effector cells involved in the pathogenesis of allergic inflammation. We conducted a study to investigate the validity of the nasal smear examination for detecting eosinophilia in patients with allergic rhinitis. Our study group was made up of 50 patients with allergic rhinitis and 50 age- and sex-matched controls without allergic rhinitis. Smears were obtained from nasal secretions in both groups and then fixed, stained, and studied under light microscopy. Statistical analysis revealed that the odds ratio for eosinophilia positivity in nasal smears in the rhinitis group was 25.61 with a 95% confidence interval of 8 to 78. The sensitivity, specificity, positive predictive value, and negative predictive value of this test were 74, 90, 88, and 77%, respectively We conclude that the nasal eosinophilia test is highly specific and moderately sensitive in diagnosing allergic rhinitis, and that it therefore can be used as an easy, noninvasive, and inexpensive procedure for screening patients and for conducting epidemiologic studies of this disorder.

Item Type: Article
Keywords: KeyWords Plus:NONALLERGIC RHINITIS; SMEAR EOSINOPHILIA; CATIONIC PROTEIN; CHILDREN; PREVALENCE; DIAGNOSIS; DISEASE; ASTHMA
Page Range: pp. 122-124
Journal or Publication Title: ENT-EAR NOSE & THROAT JOURNAL
Abstract and Indexing: ISI, Pubmed, Scopus
Quartile : Q4
Volume: 91
Number: 3
Publisher: web of science,pubmed,scopus
Depositing User: خانم مریم زرقانی
URI: http://repository.zums.ac.ir/id/eprint/1359

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