Repository of Research and Investigative Information

Repository of Research and Investigative Information

دانشگاه علوم پزشکی و خدمات بهداشتی درمانی زنجان

Xenoderm Versus 1% Silver Sulfadiazine in Partial-thickness Burns

(2009) Xenoderm Versus 1% Silver Sulfadiazine in Partial-thickness Burns. ASIAN JOURNAL OF SURGERY. pp. 234-239.

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Abstract

OBJECTIVE: The aim of this clinical trial was to evaluate the effectiveness Of using lyophilised porcine skin (Xenoderm) compared with 1% silver sulfadiazine (SSD) in partial-thickness burns with regard to Wound infection, length of hospital stay, number of dressings and doses of analgesics used (oral and injection). METHODS: A total of 78 burns patients were included in this randomised study; their burns were caused by scalds or flames. They had second degree burns and had a burn area of 10-60% of total body Surface area (TBSA). Thirty-seven patients were treated with daily washing, followed by topical application of SSD dressing (the SSD group) and 39 with a biological dressing, i.e. Xenoderm (the Xenoderm group). The differences were evaluated using unpaired Student's t-test, Mann-Whitney U test and Chi-square test. RESULTS: There,were no significant differences between the two groups with respect to age, gender, TBSA, cause of burn, and thickness of the burn or burn sire. But there were significant differences regarding degree Of wound infection, length of hospital stay, number of used dressings and given doses of analgesics. CONCLUSION: Xenoderm seems to be more effective than SSD dressing in terms of pain control, degree of wound infection, used wound dressings and length of hospital stay for partial-thickness burns. Prospective randomised studies are now necessary to compare possible reductions in the use of split thickness skin grafts and re-epithelialisation times. Asian J Surg 2009;32(4):234-9]

Item Type: Article
Keywords: biological dressing; partial-thickness burns; silver sulfadiazine; Xenoderm
Page Range: pp. 234-239
Journal or Publication Title: ASIAN JOURNAL OF SURGERY
Abstract and Indexing: ISI, Pubmed, Scopus
Quartile : Q2
Volume: 32
Number: 4
Publisher: web of science,pubmed,scopus
Depositing User: خانم مریم زرقانی
URI: http://repository.zums.ac.ir/id/eprint/1050

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